Ben Corry

The paper identifies a small molecule inhibitor of AtSAL1, demonstrating its ability to modulate PAP signaling and enhance stress tolerance in Arabidopsis without genetic pleiotropy.

The paper identifies two new mutations in PfFNT conferring resistance to MMV007839 and shows how these mutations destabilize inhibitor binding.

This study evaluates AlphaFold2-Multimer and AlphaFold3's ability to predict oligomeric states of proteins, showing their utility but also highlighting limitations for proteins without structural representatives in the training set.

This study shows that TamB transfers lipids through a hydrophobic groove connecting inner and outer membranes in Gram-negative bacteria, with lipid release dependent on TamA binding.

The paper identifies how 3-mer oligonucleotides with base and sugar modifications modulate TLR7 and TLR8 responses, leading to the development of a dual inhibitory oligonucleotide for autoimmune disease.

The paper identifies 2'-O-methyl-guanosine RNA fragments as natural antagonists of TLR7/8, preventing auto-immunity by inhibiting TLR signaling.

This paper identifies a proton transfer mechanism in the malaria parasite lactate/H+ symporter, showing it functions as a transporter without conformational changes and can switch between transporter and channel modes.

The paper shows TMEM63 proteins function as mechanically activated lipid scramblases, modulated by cholesterol, contributing to membrane resilience.

The paper uses AlphaFold2 to predict structures of voltage-gated ion channel VSDs and pore regions, showing diverse conformations but noting discrepancies with experimental data.

This study reveals how KIDINS220 and InsP8 regulate XPR1's phosphate export through structural mechanisms and evolutionary insights.

This study presents high-resolution structures of C. albicans Cdr1 in multiple states and uses simulations and evolutionary analysis to elucidate its transport mechanism and drug resistance.