Ruitao Jin

The paper identifies how 3-mer oligonucleotides with base and sugar modifications modulate TLR7 and TLR8 responses, leading to the development of a dual inhibitory oligonucleotide for autoimmune disease.

The paper identifies 2'-O-methyl-guanosine RNA fragments as natural antagonists of TLR7/8, preventing auto-immunity by inhibiting TLR signaling.

This study reveals how KIDINS220 and InsP8 regulate XPR1's phosphate export through structural mechanisms and evolutionary insights.

This study presents high-resolution structures of C. albicans Cdr1 in multiple states and uses simulations and evolutionary analysis to elucidate its transport mechanism and drug resistance.