Thermal proteome profiling identifies glucose binding proteins involved in metabolic disease
Lindsey M. Meservey, Ian Ferguson, Vivian B. Tien, Luca Ducoli, Weili Miao, David M. Lu, Suhas Srinivasan, Vanessa Lopez-Pajares, Douglas F. Porter, Zhongwen Cao, Yisheng Wang, Paul A. Khavari
This study identifies glucose-binding proteins TSC22D4 and IGF2BP2 using thermal proteome profiling, showing their roles in metabolic disease and insulin secretion.
bioRxiv · May 6, 2025 · PreprintBiochemistry