Weili Miao

Disease-Linked Regulatory DNA Variants and Homeostatic Transcription Factors in Epidermis

The paper identifies disease-linked regulatory DNA variants and their impact on epidermal homeostasis by analyzing SNVs, TF binding, and gene dysregulation in polygenic skin diseases.

Thermal proteome profiling identifies glucose binding proteins involved in metabolic disease

This study identifies glucose-binding proteins TSC22D4 and IGF2BP2 using thermal proteome profiling, showing their roles in metabolic disease and insulin secretion.

irCLIP-RNP and Re-CLIP reveal patterns of dynamic protein associations on RNA

The paper introduces irCLIP-RNP and Re-CLIP methods to identify dynamic RNA-protein assemblies, revealing new patterns of RBP-RNA associations and EGF-induced remodeling.

Mitochondrial Raf1 Regulates Glutamine Catabolism

This paper identifies Raf1 within mitochondria where it interacts with GLS to regulate glutamine catabolism and tumorigenesis, independent of MAPK signaling.

Glucose modulates transcription factor dimerization to enable tissue differentiation

This study shows glucose acts as a morphogen that modulates transcription factor dimerization during tissue differentiation.

Modified forms of easyCLIP

This paper improves the easyCLIP protocol by addressing its limitations and providing a more reproducible analysis workflow.