Author

Zhuanzhuan Che

Southeast University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Chengqi LiniD· 3 shared Haitong FangiD· 3 shared Zhuojuan LuoiD· 3 shared Chenghao GuoiD· 2 shared Ke Fang· 2 shared Peng XieiD· 2 shared Xiaoxu LiuiD· 2 shared Chen CheniD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMolecular Biology

Chengqi LinORCID

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3 papers

Recent·Most cited

Epigenetic delineation of the earliest cardiac lineage segregation by single-cell multi-omics

Peng Xie, Xu Jiang, Jingjing He, Qingyun Pan, Xianfa Yang, Yanying Zheng, Zhuanzhuan Che, Wenli Fan, Chen Wu, Weiheng Zheng, Shuhan Si, Kun Gao, Shiqi Zhu, Ke Fang, Haitong Fang, , Chengqi Lin

The paper uses single-cell multi-omics to study early cardiac lineage specification in mouse embryos, identifying key transcription factors and regulatory networks.

bioRxiv · May 17, 2024 · PreprintMolecular Biology

Distinct roles of the two SEC scaffold proteins, AFF1 and AFF4, in regulating RNA Pol II transcription elongation

Zhuanzhuan Che, Xiaoxu Liu, Qian Dai, Ke Fang, Chenghao Guo, Junjie Yue, Haitong Fang, Peng Xie, Zhuojuan Luo, Chengqi Lin

This study shows AFF1 and AFF4 have distinct roles in RNA Pol II transcription elongation, with AFF1 upstream and AFF4 downstream of TSS, and they function antagonistically to regulate transcription.

Journal of Molecular Cell Biology · Jul 31, 2023Peer-reviewedGenomics

RNF219 interacts with CCR4-NOT in regulating stem cell differentiation

Hao Du, Chen Chen, Yan Wang, Yang Yang, Zhuanzhuan Che, Xiaoxu Liu, Siyan Meng, Chenghao Guo, Manman Xu, Haitong Fang, Fengchao Wang, Chengqi Lin, Zhuojuan Luo

This study identifies RNF219 as an interacting partner of the CCR4-NOT deadenylase complex, showing its role in regulating RNA stability and ES cell differentiation.

Journal of Molecular Cell Biology · Oct 21, 2020Peer-reviewedMolecular Biology