Xianfa Yang

The paper shows that the cloacal outgrowth coordinates bladder and umbilical artery development through Shh and Wnt2 signals in humans and mice.

This study constructs a spatiotemporal regulatory framework for mouse gastrulation using multi-omic data and reveals mechanisms of lineage commitment and symmetry breaking.

The paper introduces Palette, a method to infer spatial gene expression from bulk RNA-seq data, and constructs DreSTEP, a resource for studying gene expression and spatial interactions in zebrafish embryos.

The paper identifies a pre-marked enhancer, p-Enh, that primes posterior tissue development in mouse embryos through interaction with the TGF-β signaling pathway.

This study identifies lncRNA-Gm26793 as a key regulator of stem cell differentiation and mouse embryogenesis through an inter-chromosomal interaction with Cubn.

The paper uses single-cell multi-omics to study early cardiac lineage specification in mouse embryos, identifying key transcription factors and regulatory networks.

The paper constructs a single-cell spatio-temporal atlas of molecular trajectories during gastrulation in mouse embryos, revealing asymmetric BMP signaling and its role in left-right body plan asymmetry.