Author

Zi-Wen Weng

National Taiwan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Danny FarhatiD· 1 shared Fatemeh RezaeiiD· 1 shared Isra F Omar· 1 shared Jyh‐Yeuan LeeiD· 1 shared Kadambari Vijay Sai· 1 shared Qing-Fang Xiao· 1 shared Shang‐Te Danny HsuiD· 1 shared Yuan‐Chih ChangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Danny FarhatORCID

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1 paper

Recent·Most cited

A Sterol-Binding Cavity Underlies Sterol Recognition and Differential Activation of the ABCG5/G8

Fatemeh Rezaei, Isra F Omar, Danny Farhat, Zi-Wen Weng, Kadambari Vijay Sai, Qing-Fang Xiao, Yuan‐Chih Chang, Shang‐Te Danny Hsu, Jyh‐Yeuan Lee

This study determines the cryo-EM structure of ABCG5/G8 with ergosterol and shows that ergosterol activates the transporter more than cholesterol or CHS, with Y432 in the aromatic clamp playing a key role.

bioRxiv · Aug 11, 2026 · PreprintBiochemistry