Neuron-astrocyte Coupling in Lateral Habenula Mediates Depressive-like Behaviors
Qianqian Xin, Junying Wang, Jinkun Zheng, Yi Jayne Tan, Xiaoning Jia, Zheyi Ni, Zijie Xu, Jiesi Feng, Zhaofa Wu, Yulong Li, Wei‐Guang Li, Huan Ma, Hailan Hu
This study identifies a stress-induced positive feedback loop in the LHb-LC axis mediated by astrocytic calcium signaling, which influences depressive-like behaviors in mice.
Cell · Apr 24, 2025Peer-reviewedNeuroscience