Author

Ziyuan Chen

University of California, BerkeleyPrimary ORCID profile (0000-0003-2832-945X · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Ziyuan CheniD1 paper · University of Michigan

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alexandria Lydecker· 1 shared Alfredo Jose Florez ArizaiD· 1 shared Ana-Florina GaliciD· 1 shared Eva NogalesiD· 1 shared Robert TjianiD· 1 shared Trinity CookisiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

Alexandria Lydecker

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1 paper

Recent·Most cited

Protein cofactors diversify PRC2 architecture and function

Trinity Cookis, Ana-Florina Galic, Ziyuan Chen, Alexandria Lydecker, Alfredo Jose Florez Ariza, Robert Tjian, Eva Nogales

This study reports cryo-EM structures of PRC2.1 complexes with different cofactors, revealing how they diversify function while maintaining conserved catalytic mechanisms.

bioRxiv · Oct 26, 2026 · PreprintBiophysics