Base editing in bovine embryos reveals a species-specific role of SOX2 in regulation of pluripotency
Lei Luo, Yan Shi, Huanan Wang, Zizengchen Wang, Yanna Dang, Shuang Li, Shaohua Wang, Kun Zhang
This study uses base editing in bovine embryos to show that SOX2 has species-specific roles in pluripotency regulation, differing from its function in mice.
PLoS Genetics · Jul 5, 2022Peer-reviewedDevelopmental Biology