ImmunologybioRxivPreprint
Cholestasis alters polarization and suppressor function of hepatic regulatory T cells.
Ramesh Kudira, Z. F. Yang, Immaculeta Osuji…·Alexander Gerhard Miethke
This study shows cholestasis shifts hepatic Tregs to a Th17 phenotype and impairs their suppressor function, with bile acid levels influencing Treg activity and liver injury.