Author

Annika Yang vom Hofe

Cincinnati Children's Hospital Medical CenterORCID 0000-0002-0490-1047Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexander Gerhard MiethkeiD· 2 shared Emily R. MiraldiiD· 2 shared Liva PfuhleriD· 2 shared Ramesh KudiraiD· 2 shared Amy E. TayloriD· 1 shared Anas BerniehiD· 1 shared Andrew T. TroutiD· 1 shared Astha MalikiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Alexander Gerhard MiethkeORCID

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2 papers

Recent·Most cited

Macrophages drive a fibrogenic gene program of periductal fibroblasts in pediatric primary sclerosing cholangitis

Yunguan Wang, David Adeleke, Xiangfei Xie, Zi F. Yang, Annika Yang vom Hofe, Manavi Singh, Astha Malik, Ramesh Kudira, Cyd M. Castro-Rojas, Liva Pfuhler, Mosab Alquraish, Pamela B. Sylvestre, Jonathan R. Dillman, Andrew T. Trout, Emily R. Miraldi, Alexander Gerhard Miethke

This study identifies macrophage-driven fibrotic gene programs in periductal fibroblasts of PSC using multi-omics data, highlighting potential therapeutic targets.

bioRxiv · Aug 14, 2025 · PreprintImmunology

Cholestasis alters polarization and suppressor function of hepatic regulatory T cells.

Ramesh Kudira, Z. F. Yang, Immaculeta Osuji, Rebekah A. Karns, Priya Bariya, Liva Pfuhler, Mary M. Mullen, Amy E. Taylor, Hongjian Ji, Celine Silva Lages, Annika Yang vom Hofe, Tiffany Shi, Srikar Pasula, Joseph A. Wayman, Anas Bernieh, , Alexander Gerhard Miethke

This study shows cholestasis shifts hepatic Tregs to a Th17 phenotype and impairs their suppressor function, with bile acid levels influencing Treg activity and liver injury.

bioRxiv · May 17, 2024 · PreprintImmunology