mm2-gb: GPU Accelerated Minimap2 for Long Read DNA Mapping
Juechu Dong, Xueshen Liu, Harisankar Sadasivan…·Satish Narayanasamy
mm2-gb accelerates Minimap2's chaining step on GPU, improving performance for long DNA reads without sacrificing accuracy.
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University of MichiganORCID 0000-0001-5016-1214Unclaimed ORCID profile · follow to get notified of new preprints
11 papers
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Juechu Dong, Xueshen Liu, Harisankar Sadasivan…·Satish Narayanasamy
mm2-gb accelerates Minimap2's chaining step on GPU, improving performance for long DNA reads without sacrificing accuracy.
Vishwaratn Asthana, Erika Martínez Nieves, Pallavi Bugga…·J. Scott VanEpps
This paper introduces a universal bacterial identification system using ITS-targeting primers that outperforms existing methods in speed, cost, and taxonomic breadth.
Tim Dunn, Justin M. Zook, James Holt, Satish Narayanasamy
This work extends vcfdist to jointly benchmark SNPs, INDELs, and SVs, showing error reductions and improved accuracy over previous methods.
Harisankar Sadasivan, Daniel Stiffler, Ajay Tirumala…·Satish Narayanasamy
DTWax optimizes the sDTW algorithm for GPU to improve sequencing speed and compute efficiency in nanopore sequencing.
The paper introduces vcfdist, a tool that improves the accuracy of benchmarking phased small variant calls in human genomes by addressing biases in variant representation and evaluation methods.
Tim Dunn, David T. Blaauw, Reetuparna Das, Satish Narayanasamy
nPoRe improves INDEL recall in nanopore sequencing by extending gap penalties in alignment, achieving 73.04% recall with no loss of precision.
Harisankar Sadasivan, Milos Maric, Eric T. Dawson…·Satish Narayanasamy
The paper accelerates Minimap2 for long read alignment on GPUs by optimizing the chaining step, achieving significant speedup and cost reduction.
Harisankar Sadasivan, Jack Wadden, Kush Goliya…·Satish Narayanasamy
RawMap is a fast and accurate classifier for filtering non-target reads in real-time nanopore sequencing, improving efficiency and reducing costs.
Jack Wadden, Brandon Newell, Joshua Bugbee…·Reetuparna Das
This paper introduces Threshold Sequencing and LAMPrey to enable ultra-rapid somatic variant detection in under 30 minutes using real-time sequencing and targeted amplification.