Izabela Figiel

This study shows human astrocytes delay neuronal maturation compared to chimpanzee astrocytes, linking astrocyte evolution to brain neoteny and disease vulnerability.

This study shows that S-palmitoylation differentially affects synaptic plasticity and neuronal spiking timing, targeting specific proteins in excitatory synapses.

The paper identifies molecular changes in human astrocytes compared to non-human primates, revealing regulatory mechanisms linked to brain evolution.

The paper investigates stress resilience in mice, showing it involves structural, functional, and molecular changes in synapses, particularly through palmitoylation of synaptic proteins and dendritic spine remodeling.

This study identifies plasmin-mediated cleavage of EphA4 at central amygdala inhibitory synapses as a mechanism controlling anxiety through modulation of GABA-receptor anchoring and dendritic spine morphology.

The paper investigates stress-induced changes in S-palmitoylation and S-nitrosylation of synaptic proteins using a mouse model and a new mass spectrometry-based approach.