Błażej Ruszczycki

Stress resilience is an active and multifactorial process manifested by structural, functional, and molecular changes in synapses

The paper investigates stress resilience in mice, showing it involves structural, functional, and molecular changes in synapses, particularly through palmitoylation of synaptic proteins and dendritic spine remodeling.

Neuronal activation affects the organization and protein composition of the nuclear speckles

This study shows neuronal activation remodels nuclear speckles' organization and protein composition in rat hippocampal neurons without causing stress or cell death, and these changes depend on transcription and splicing.

3dSpAn: an interactive software for 3D segmentation and analysis of dendritic spines

3dSpAn is a software tool for 3D segmentation and morphological analysis of dendritic spines, addressing segmentation and quantification challenges using multiscale algorithms and feature extraction.

An important role of the interplay between Bdnf transcription and histone acetylation in epileptogenesis

The paper investigates the relationship between Bdnf transcription and histone acetylation in epilepsy, finding that Bdnf repositioning correlates with epileptic traits and is influenced by transcriptional activity and histone deacetylase inhibition.

Ultrastructural Visualization of 3D Chromatin Folding Using Serial Block-Face Scanning Electron Microscopy and In Situ Hybridization (3D-EMISH)

This paper develops a new electron microscopy method to visualize 3D chromatin folding at ultra-resolution in human cells and finds high heterogeneity in chromatin structures.