Author

Melinda M. Diver

Memorial Sloan Kettering Cancer CenterORCID 0000-0001-5037-7322Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:structural biology· 2 Research Focus:cell signaling & trafficking· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Qinyu ZhuiD· 2 shared Henning Jacob JesseniD· 1 shared Madeleine F. YaggiiD· 1 shared Nikolaus JorkiD· 1 shared Omar AlmakkiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersBiophysics

Qinyu ZhuORCID

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2 papers

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedJul 28, 2026

Structural and mechanistic insights into SLC34 phosphate import

Qinyu Zhu, Omar Almakki, Melinda M. Diver

This study presents cryo-EM structures of SLC34A2, revealing its architecture, substrate binding sites, and transport mechanism, with implications for phosphate homeostasis and therapeutic targeting.

DOI 10.1073/pnas.2602077123

humanstructural biology

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BiophysicsNature CommunicationsPeer-reviewedMar 20, 2025

Transport and InsP8 activation mechanisms of the human inorganic phosphate exporter XPR1

Qinyu Zhu, Madeleine F. Yaggi, Nikolaus Jork…·Melinda M. Diver

This study elucidates the transport mechanism of XPR1 and how InsP8 activation regulates its function through structural and functional analysis.

13 citations

humanstructural biology

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