Author

Omar Almakki

University of ChicagoORCID 0009-0001-5545-5606Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Ivan P. G. MoskowitziD· 2 shared Kohta IkegamiiD· 2 shared Alexis V. StutzmaniD· 1 shared Atsuki EniD· 1 shared Briana Thomas· 1 shared Brigitte LaForestiD· 1 shared Hanumakumar Bogireddi· 1 shared Jason D. Lieb· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Ivan P. G. MoskowitzORCID

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3 papers

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedJul 28, 2026

Structural and mechanistic insights into SLC34 phosphate import

Qinyu Zhu, Omar Almakki, Melinda M. Diver

This study presents cryo-EM structures of SLC34A2, revealing its architecture, substrate binding sites, and transport mechanism, with implications for phosphate homeostasis and therapeutic targeting.

DOI 10.1073/pnas.2602077123

humanstructural biology

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Molecular BiologyCell ReportsPeer-reviewedMay 29, 2024

Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice

Atsuki En, Hanumakumar Bogireddi, Briana Thomas…·Kohta Ikegami

The paper shows that NE ruptures occur before ECM signaling and disease in Lamin-cardiomyopathy mice without activating cGAS-STING.

40 citationstop 2%

mouseexperimental assay

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GeneticsDevelopmental CellPeer-reviewedMar 1, 2020

Phosphorylated Lamin A/C in the nuclear interior binds active enhancers associated with abnormal transcription in progeria

Kohta Ikegami, Stefano Secchia, Omar Almakki…·Ivan P. G. Moskowitz

114 citationstop 4%

humanbulk RNA-seq

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