Cell BiologyBloodPeer-reviewed
PERK Signaling Maintains Hematopoietic Stem Cell Pool Integrity under Endoplasmic Reticulum Stress by Promoting Proliferation
Manxi Zheng, Qinlu Peng, Erin M. Kropp…·Lu Liu
This study shows PERK signaling promotes HSC proliferation under ER stress to maintain stem cell pool integrity by activating mTOR, without relying on apoptosis.
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