Author

Massimo Reconditi

University of FlorenceORCID 0000-0001-5065-924XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1 Organism:rat· 1 Assay:structural biology· 1

Frequent Co-Authors

Irene PerticiiD· 3 shared Pasquale BiancoiD· 3 shared Elena BattirossiiD· 2 shared Johannes N. GreveiD· 2 shared Nataliya Di DonatoiD· 2 shared Vincenzo LombardiiD· 2 shared Á. AltorjayiD· 1 shared Andréa VargaiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersNeuroscience

Irene PerticiORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 12, 2026

The distinct role of actin isoforms on mechanosensing-based maturation of hiPSC-derived neurons unveiled by isoform-specific mutations

Elena Battirossi, Indra Niehaus, Irene Pertici…·Pasquale Bianco

This study investigates the role of beta- and gamma-actin isoforms in neuronal mechanotransduction using mutations linked to BWCFF syndrome, revealing distinct functional consequences.

DOI 10.64898/2026.05.11.724094

humanexperimental assay

𝕏 PostBluesky

BiophysicsThe FASEB JournalPeer-reviewedJan 5, 2026

The Baraitser-Winter Cerebrofrontofacial Syndrome recurrent R196H variant in cytoplasmic β-actin impairs its cellular polymerization and stability

Éva Gráczer, Elena Battirossi, Tamás Bozó…·Andréa Varga

This study investigates the R196H mutation in β-actin, showing it reduces F-actin content and cell stiffness, weakens actin-membrane attachment, and impairs cofilin interaction.

3 citationstop 3%

humanproteomics

𝕏 PostBluesky

PhysiologyProceedings of the National Academy of SciencesPeer-reviewedDec 4, 2024

An integrated picture of the structural pathways controlling the heart performance

Ilaria Morotti, Marco Caremani, Matteo Marcello…·Marco Linari

The paper revises the mechanosensing hypothesis of heart function using X-ray diffraction data and cryo-EM structures, identifying structural changes in thick filaments that modulate motor activation and heart performance.

13 citations

ratstructural biology

𝕏 PostBluesky