PhysiologyProceedings of the National Academy of SciencesPeer-reviewed
An integrated picture of the structural pathways controlling the heart performance
Ilaria Morotti, Marco Caremani, Matteo Marcello…·Marco Linari
The paper revises the mechanosensing hypothesis of heart function using X-ray diffraction data and cryo-EM structures, identifying structural changes in thick filaments that modulate motor activation and heart performance.
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