Author

Christian Daniel Mutti

University of CambridgeORCID 0000-0001-5091-5055Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Lindsey Van HauteiD· 3 shared Michal A. MinczukiD· 3 shared Pedro Silva-PinheiroiD· 2 shared Aaron R. D’SouzaiD· 1 shared Christopher A. PowelliD· 1 shared Isabel Dowling· 1 shared Joanna RorbachiD· 1 shared Jose Domingo Barrera-PaeziD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersBioinformatics

Lindsey Van HauteORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJun 5, 2026

Development of the Mitochondrial Base Editor Analysis Package (MitoBEAP).

Christian Daniel Mutti, Pavel A. Nash, Pedro Silva-Pinheiro…·Lindsey Van Haute

The paper introduces MitoBEAP, an R package for analysing next-generation sequencing data from mitochondrial base-edited samples to assess off-target effects.

1 citation

humanwhole-genome sequencing

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BioengineeringbioRxivPreprintDec 10, 2024

Mitochondrial adenine base editing of mouse somatic tissues via adeno-associated viral delivery

Christian Daniel Mutti, Lindsey Van Haute, Lucia Luengo-Gutierrez…·Michal A. Minczuk

This study tests mitochondrial adenine base editing in mouse tissues via AAV delivery, finding low and modestly increasing editing efficiency over time.

DOI 10.1101/2024.12.10.627690

mouseDNA methylation

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Molecular BiologyNucleic Acids ResearchPeer-reviewedMay 6, 2021

YbeY is required for ribosome small subunit assembly and tRNA processing in human mitochondria

Aaron R. D’Souza, Lindsey Van Haute, Christopher A. Powell…·Michal A. Minczuk

This study identifies YbeY as essential for mitochondrial ribosome small subunit assembly and tRNA processing, showing its dual role in coupling these processes.

20 citations

humanexperimental assay

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