Author

Marc Lewitzky

Martin Luther University Halle-WittenbergORCID 0000-0001-5118-2623Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Stephan M. FelleriD· 2 shared Alaa ShaikhqasemiD· 1 shared Ali HmedatiD· 1 shared C. ParthieriD· 1 shared Constanze Breithaupt· 1 shared Daniel V. EbneriD· 1 shared Farzad HamdiiD· 1 shared Felix Wiebe· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Stephan M. FellerORCID

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2 papers

Recent·Most cited

BiochemistryStructurePeer-reviewedDec 22, 2025

Mechanism of SHP2 activation by bis-Tyr-phosphorylated Gab1

Lisa Machner, Alaa Shaikhqasem, Tobias Gruber…·Milton T. Stubbs

This study identifies how bis-Tyr-phosphorylated Gab1 activates SHP2 by binding both SH2 domains and inducing structural changes.

6 citations

experimental assayprotein folding & dynamics

𝕏 PostBluesky

Cancer BiologyCell Communication and SignalingPeer-reviewedJun 19, 2025

The Src family kinase inhibitor drug Dasatinib and glucocorticoids display synergistic activity against tongue squamous cell carcinoma and reduce MET kinase activity

Ali Hmedat, Jessica B. Doondeea, Daniel V. Ebner…·Marc Lewitzky

This paper shows that Dasatinib and glucocorticoids work together to kill tongue squamous cell carcinoma cells by reducing MET kinase activity and inducing cell cycle arrest and senescence.

6 citationstop 5%

humanproteomics

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