Author

Jason Yi

National Institutes of HealthORCID 0000-0001-5131-6767Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Aakriti Kumar· 1 shared Alison Ma· 1 shared Andy D. TraniD· 1 shared Daria J. HazudaiD· 1 shared Dinesh P. de Alwis· 1 shared Gevorg GrigoryaniD· 1 shared Hetvi J. Desai· 1 shared Jiahe Li· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioengineering

Aakriti Kumar

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BioengineeringbioRxivPreprintOct 29, 2026

Refactored intracellular domains enhance CAR expression and function

Liam Bai, Aakriti Kumar, Hetvi J. Desai…·Jason Yi

This paper uses AI agents to design and refine CAR intracellular domains, resulting in a compact ICD that improves CAR expression and function.

DOI 10.64898/2026.10.28.762481

experimental assay

𝕏 PostBluesky

ImmunologyFrontiers in ImmunologyPeer-reviewedDec 24, 2024

CD28 Shapes T Cell Receptor Signaling by Regulating ZAP70 Activation and Lck Dynamics

Kumarkrishna Raychaudhuri, Rohita Rangu, Alison Ma…·Lawrence E. Samelson

This study shows CD28 co-stimulation accelerates ZAP70 recruitment and activation in TCR microclusters by enhancing Lck dynamics and spatial separation of Lck species.

16 citations

humanproteomics

𝕏 PostBluesky