Pharmacology & ToxicologyToxicological SciencesPeer-reviewed
Acute Exposure to Perfluorooctanoic Acid (PFOA) During Cardiomyogenesis disrupts Transcriptional and Electrophysiological Profiles in Differentiated Myocytes
Tomoko Ishikawa, Christopher Wayne Clark, Anagha Tapaswi…·Laurie Kathleen Svoboda
This study shows that PFOA exposure during cardiomyocyte differentiation alters gene expression and electrophysiological function in hiPSC-CM, with effects lasting after exposure stops.
DOI 10.1093/toxsci/kfag107