Stress granule formation helps to mitigate neurodegeneration
M. Rebecca Glineburg, Evrim Yildirim, Nicolás Gómez, Genesis Rodriguez, Jaclyn Pak, Xingli Li, Christopher H. Altheim, Jacob Waksmacki, Gerald M. McInerney, Sami J. Barmada, Peter K. Todd
This study investigates the role of stress granule formation in neurodegeneration, finding that reducing stress granules exacerbates disease phenotypes in models of ataxia, ALS, and FTD.
Nucleic Acids Research · Jul 17, 2024Peer-reviewedNeuroscience