Molecular BiologybioRxivPreprint
Structures of the human transcription factor brachyury offer insights into DNA recognition, and identify small molecule binders for the development of degraders for cancer therapy
Joseph A. Newman, Angeline E. Gavard, Nergis Imprachim…·David Harold Drewry
This study determines the structure of human brachyury, identifies DNA binding insights and a G177D variant, and discovers small molecule binders for potential cancer therapy.
DOI 10.1101/2024.06.06.597736