Author

Charles E. de Bock

ORCID 0000-0001-5182-8535Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Abdul MannaniD· 1 shared Anoop K. EnjetiiD· 1 shared Brooke M. Harvey· 1 shared Carlos RiverosiD· 1 shared Charley Lawlor-O’Neill· 1 shared Danielle R. BondiD· 1 shared Ellise A. Roper· 1 shared Heather C. MurrayiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Abdul MannanORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivJan 30, 2024

Hypomethylating agents induce epigenetic and transcriptional heterogeneity with implications for AML cell self-renewal.

Danielle R. Bond, Sean M. Burnard, Kumar Uddipto…·Heather J. Lee

This study shows that hypomethylating agents induce epigenetic and transcriptional heterogeneity in AML cells, with some cells retaining methylation and showing increased self-renewal, and identifies statins as a potential co-treatment to enhance HMA efficacy.

DOI 10.1038/s41375-025-02693-5

humanDNA methylation

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