Cancer BiologyCancer Immunology ResearchPeer-reviewed
Periductal Fibroblast Density Defines Lymphocyte Exclusion via a CD44-Dependent Stromal Checkpoint in Pancreatic Cancer
Zoe X. Malchiodi, Alexander A. Lekan, Robert K. Suter…·Louis M. Weiner
The paper identifies periductal fibroblast density as a key factor in immune exclusion in pancreatic cancer, showing that CD44-dependent stromal checkpoints restrict leukocyte access to tumor epithelium.
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