Author

Helena Brentani

Universidade de São PauloORCID 0000-0001-5192-4682Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:GWAS / association mapping· 3 Assay:GWAS summary statistics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:scRNA-seq· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Bernadette CulleniD· 2 shared Carolina CappiiD· 2 shared Cristina BarlassinaiD· 2 shared Donald W. BlackiD· 2 shared Dongmei YuiD· 2 shared Edwin H. CookiD· 2 shared Kathleen D. AsklandiD· 2 shared Maria Cristina CavalliniiD· 2 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Bernadette CullenORCID

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4 papers

Recent·Most cited

Genetic & Genomic MedicineResearch at the University of Copenhagen (University of Copenhagen)Peer-reviewedJan 1, 2025

Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder

Nora I Strom, Zachary F Gerring, Marco Galimberti…·Bjarne K. A. Hansen

This study identifies 30 genome-wide significant loci for obsessive-compulsive disorder (OCD) using a large GWAS, linking risk to specific brain cell types and shared genetic risk with other psychiatric and non-psychiatric traits.

9 citations

humanGWAS summary statistics

Genetic & Genomic MedicinemedRxivPreprintSep 9, 2022

Assessing the risk stratification of breast cancer polygenic risk scores in two Brazilian samples

Rodrigo Barreiro, Tatiana Ferreira de Almeida, Catarina dos Santos Gomes…·Michel Satya Naslavsky

This study evaluates the transferability of a breast cancer polygenic risk score in two Brazilian admixed cohorts compared to UK Biobank data, finding inflated PRS distributions and equivalent predictive power in case-control comparisons.

DOI 10.1101/2022.09.09.22279721

humanwhole-genome sequencing

GenomicsTranslational PsychiatryPeer-reviewedFeb 2, 2021

Genome-wide Association Study of Pediatric Obsessive-Compulsive Traits: Shared Genetic Risk between Traits and Disorder

Christie L. Burton, Mathieu Lemire, Bowei Xiao…·Andrew D. Paterson

This study identifies a genome-wide significant variant for OC traits and shows shared genetic risk between OC traits and OCD.

50 citations

humanGWAS summary statistics

Developmental BiologybioRxivPreprintAug 29, 2020

A single cell trajectory of human archetypal pluripotent stem cell differentiation to trophoblast stem cells reveals induction of endogenous BMP5/7 and GATA3 without transitioning through a naive state

Ethan Tietze, Amilton de Lima Barbosa, Bruno Henrique Silva Araújo…·Jennifer A. Erwin

This paper shows that primed human pluripotent stem cells can differentiate to trophoblast stem cells without becoming naive, using specific signaling conditions and revealing a transcriptional network involving BMP5/7 and GATA3.

DOI 10.1101/2020.08.29.273425

humanscRNA-seq