This paper conducts a GWAS of subclinical obsessive-compulsive symptoms (OCS) in 33,943 individuals, finding polygenic risk and genetic overlap with OCD.

1 citation

humanGWAS summary statistics

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GenomicsTranslational PsychiatryPeer-reviewedFeb 2, 2021

Genome-wide Association Study of Pediatric Obsessive-Compulsive Traits: Shared Genetic Risk between Traits and Disorder

Christie L. Burton, Mathieu Lemire, Bowei Xiao…·Andrew D. Paterson

This study identifies a genome-wide significant variant for OC traits and shows shared genetic risk between OC traits and OCD.

50 citations

humanGWAS summary statistics

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GeneticsTranslational PsychiatryPeer-reviewedApr 27, 2020

Shared genetic etiology between obsessive-compulsive disorder, obsessive-compulsive symptoms in the population, and insulin signaling

Janita Bralten, Joanna Widomska, Ward De Witte…·Geert Poelmans

The paper identifies shared genetic risk factors between OCD, population-based OCS, and insulin signaling traits, suggesting a common etiological mechanism.

35 citations

humanGWAS summary statistics

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BioinformaticsPLoS Computational BiologyPeer-reviewedJan 10, 2019

Whole Genomes Define Concordance of Matched Primary, Xenograft, and Organoid Models of Pancreas Cancer

Deena M.A. Gendoo, Robert Edward Denroche, Amy Xin Wei Zhang…·Benjamin Haibe‐Kains

The paper compares whole-genome data from primary pancreatic cancer, xenografts, and organoids to assess genetic concordance across different models.

55 citationstop 5%

humanwhole-genome sequencing

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