Christie L. Burton

Association of Brain Structural Measurements and Polygenic Risk Scores with Obsessive-Compulsive Symptoms in Adolescents Diagnosed with Obsessive-Compulsive Disorder, Attention-Deficit/Hyperactivity Disorder, Anxiety, Depression, Autism and Tic Disorders

The paper examines the association between polygenic risk scores, structural brain measurements, and obsessive-compulsive symptoms in adolescents with various psychiatric diagnoses.

Genome-Wide Association Study of Obsessive-Compulsive Symptoms including 33,943 individuals from the general population

This paper conducts a GWAS of subclinical obsessive-compulsive symptoms (OCS) in 33,943 individuals, finding polygenic risk and genetic overlap with OCD.

Gene copy number variation in pediatric mental illness in a general population

The paper investigates the association between gene copy number variation and mental health traits in children, finding links to ADHD, OCD, and cognitive biomarkers.

Genome-wide Association Study of Pediatric Obsessive-Compulsive Traits: Shared Genetic Risk between Traits and Disorder

This study identifies a genome-wide significant variant for OC traits and shows shared genetic risk between OC traits and OCD.

Examining sex-differentiated genetic effects across neuropsychiatric and behavioral traits

The paper examines sex-differentiated genetic effects across neuropsychiatric and behavioral traits using GWAS summary statistics and finds small, polygenic sex differences with enriched neuron-related genes.

Characterization of Mice Bearing Humanized Androgen Receptor Genes (h/mAr) Varying in Polymorphism Length

This study characterizes the effects of varying humanized androgen receptor Q tract lengths on brain anatomy and behavior in mice, finding non-linear neuroanatomical changes and no behavioral effects.

Shared genetic etiology between obsessive-compulsive disorder, obsessive-compulsive symptoms in the population, and insulin signaling

The paper identifies shared genetic risk factors between OCD, population-based OCS, and insulin signaling traits, suggesting a common etiological mechanism.

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

Genome-wide association meta-analysis of 20,183 ADHD cases and 35,191 controls finds 12 significant loci; signal concentrates in conserved regions, constrained genes, and CNS regulatory elements.

Utility of the SWAN Scale for ADHD Trait-Based Genetic Research: A Validity and Polygenic Risk Study

The paper validates the SWAN Scale as a tool for ADHD trait-based genetic research, showing it predicts ADHD diagnoses and is linked to ADHD polygenic risk.

Examination of the Shared Genetic Basis of Anorexia Nervosa and Obsessive-Compulsive Disorder

This study investigates the shared genetic basis of anorexia nervosa and obsessive-compulsive disorder using a cross-disorder GWAS, finding a significant genetic correlation and associations with psychiatric and metabolic traits.

Factor Structure and Heritability of Obsessive-Compulsive Traits in Children and Adolescents in the General Population

The paper investigates the factor structure and heritability of obsessive-compulsive traits in children and adolescents using the TOCS, identifying six dimensions and estimating heritability ranges.