Author

Nathanael I. Singh

City University of New YorkORCID 0000-0001-5192-747XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Ali EbrahimiD· 1 shared Aliki PerdikariiD· 1 shared Blake T. RileyiD· 1 shared D. A. KeedyiD· 1 shared Dinesh Singh ShahiD· 1 shared Elana HenningiD· 1 shared I. Sadaf FarooqiiD· 1 shared Jackson W. MorrisiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Ali EbrahimORCID

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1 paper

Recent·Most cited

BiophysicsJournal of Biological ChemistryPeer-reviewedOct 23, 2025

Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy

Aliki Perdikari, Virgil A. Woods, Ali Ebrahim…·D. A. Keedy

The paper identifies functional PTP1B variants in thin individuals and uses structural biology to reveal allosteric sites for obesity drug development.

8 citations

humanprotein structure

𝕏 PostBluesky