Cell BiologybioRxivPreprint
Identification of AB8939, a novel synthetic microtubule destabilizer and ALDH inhibitor that overcomes multidrug resistance in tumor cells as a drug candidate for the treatment of refractory acute myeloid leukemia
Martine Humbert, Sébastien Letard, Armelle Goubard…·Patrice C. Dubreuil
This paper identifies AB8939, a novel drug that targets microtubules and ALDH enzymes, showing efficacy against drug-resistant AML cells and models.
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