Author

Alain Moussy

AB Science (France)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Colin D. MansfieldiD· 3 shared Laurent GrosiD· 2 shared Olivier HermineiD· 2 shared Patrick VermerschiD· 2 shared Abdellah Benjahad· 1 shared Armelle GoubardiD· 1 shared Benoı̂t GigantiD· 1 shared Bérengère Hajem· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Colin D. MansfieldORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Masitinib is an oral, brain penetrant inhibitor of microglial and mast cell activity with neuroprotective potential in progressive forms of multiple sclerosis

Patrick Vermersch, Alain Moussy, Colin D. Mansfield, Olivier Hermine

This paper demonstrates that masitinib achieves sufficient CNS concentrations to inhibit key targets in progressive MS, showing neuroprotective effects and potential as a treatment.

bioRxiv · Jul 7, 2026 · PreprintNeuroscience

Identification of AB8939, a novel synthetic microtubule destabilizer and ALDH inhibitor that overcomes multidrug resistance in tumor cells as a drug candidate for the treatment of refractory acute myeloid leukemia

Martine Humbert, Sébastien Letard, Armelle Goubard, Camille Montersino, Stéphane Audebert, Émilie Baudelet, Bérengère Hajem, Manuel L Neves, Samila Siavioshian, Paloma F. Varela, Benoı̂t Gigant, E. Rebuffet, Pascal Verdier‐Pinard, Rémy Castellano, Yves Collette, , Patrice C. Dubreuil

This paper identifies AB8939, a novel drug that targets microtubules and ALDH enzymes, showing efficacy against drug-resistant AML cells and models.

bioRxiv · Dec 12, 2025 · PreprintCell Biology

Masitinib Limits Neuronal Damage, as Measured by Serum Neurofilament Light Chain Concentration, in a Model of Neuroimmune-Driven Neurodegenerative Disease

Olivier Hermine, Laurent Gros, Truong-An Tran, Lamya Loussaief, Kathleen Flosseau, Alain Moussy, Colin D. Mansfield, Patrick Vermersch

PLoS ONE · May 14, 2025Peer-reviewedNeuroscience