Xuefei Yuan

This study uses deep learning to predict cis-regulatory effects of human-specific mutations across 305 tissues, revealing their role in gene expression evolution.

This study investigates the evolutionary origins and dynamics of liver cell architecture across mammals, revealing conserved zonation and rapid evolutionary turnover in zonated genes.

This study presents a single-nucleus RNA-sequencing atlas of the postnatal shark retina, identifying 22 cell types and providing insights into retinal evolution.

This study identifies GATA4/5/6 as conserved regulators of cardiac versus pharyngeal mesoderm fate by analyzing single-cell gene expression in zebrafish and Ciona.

The paper identifies conserved enhancers active early in zebrafish heart development that recapitulate human expression patterns, suggesting ancient regulatory mechanisms.

This study shows Hey2 restricts SHF progenitor addition to the zebrafish heart, preventing excessive myocardial cell growth and congenital heart defects.