Ian C. Scott

This study investigates the role of Mob4, a STRIPAK complex component, in zebrafish vascular development and stability, revealing defects similar to cerebral cavernous malformation.

This study identifies GATA4/5/6 as conserved regulators of cardiac versus pharyngeal mesoderm fate by analyzing single-cell gene expression in zebrafish and Ciona.

The paper creates a zebrafish model of SPEG-related centronuclear myopathy that replicates human disease features and identifies shared pathomechanisms across CNM subtypes.

The paper develops and benchmarks in vivo TurboID and miniTurbo labeling in zebrafish embryos for proximity-dependent biotinylation, enabling protein discovery in living vertebrates.

The paper identifies conserved enhancers active early in zebrafish heart development that recapitulate human expression patterns, suggesting ancient regulatory mechanisms.

This study identifies Ddx39a as essential for myocyte and lens development in zebrafish by affecting mRNA splicing and gene regulation.

This study shows Hey2 restricts SHF progenitor addition to the zebrafish heart, preventing excessive myocardial cell growth and congenital heart defects.