Julia Schmidt

A multi-omics atlas of human hindbrain development

This paper creates a multi-omics atlas of human hindbrain development, revealing cellular diversity, regulatory programs, and disease relevance.

The evolution of gene regulation in mammalian cerebellum development

This study identifies conserved and diverged gene regulatory networks in mammalian cerebellum development using single-nucleus gene expression and chromatin accessibility data from six species.

The origin and molecular evolution of the mammalian liver cell architecture

This study investigates the evolutionary origins and dynamics of liver cell architecture across mammals, revealing conserved zonation and rapid evolutionary turnover in zonated genes.

The evolution of gene regulatory programs controlling gonadal development in primates

This study analyzes gene regulatory programs in primate gonads, finding shared and species-specific regulatory dynamics and candidate genes for sex development disorders.

Developmental origins and evolution of pallial cell types and structures in birds

The paper characterizes the avian pallium's cell types and evolution using single-cell and spatial transcriptomics, revealing conserved and divergent features across amniotes.

A single-nucleus RNA sequencing atlas of the postnatal retina of the shark Scyliorhinus canicula

This study presents a single-nucleus RNA-sequencing atlas of the postnatal shark retina, identifying 22 cell types and providing insights into retinal evolution.

Cell-state plasticity drives heterogeneity in Group 3/4 medulloblastoma

This study identifies cell-state plasticity as a driver of heterogeneity in Group 3/4 medulloblastomas, showing that transcription factor perturbation can redirect tumor cells along different differentiation trajectories.