Author

Simon Stücheli

University of BaselORCID 0000-0001-5206-4477Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Christoph SchultheißiD· 2 shared Heinz Philipp LaubliiD· 2 shared Mascha BinderiD· 2 shared Andreas Zingg· 1 shared Anne EugsteriD· 1 shared Benjamin KasendaiD· 1 shared Claudia FischeriD· 1 shared Claudia Fischer· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Christoph SchultheißORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologyHaematologicaPeer-reviewedSep 11, 2025

IGLV3-21-R110-directed bispecific antibodies activate T cells and promote killing in a high-risk subset of chronic lymphocytic leukemia

Claudia Fischer, Shih‐Shih Chen, Johanna Nimmerfroh…·Mascha Binder

This study develops bispecific antibodies targeting IGLV3-21R110 to selectively kill high-risk CLL cells while sparing healthy B cells and stem cells.

1 citation

humanproteomics

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ImmunologybioRxivPreprintJan 20, 2025

CAR T cell engineering impacts antigen-independent activation and co-inhibition

Simon Stücheli, Christoph Schultheiß, Paul Schmidt-Barbo…·Mascha Binder

This study compares viral and non-viral methods for CAR T cell engineering, finding that non-viral SB transposition alters T cell activation and co-inhibition markers, with CAR design and donor type influencing outcomes.

DOI 10.1101/2025.01.20.631849

humanflow cytometry

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