Anne Eugster

This paper explores using anti-TSHR autoantibodies to create bispecific antibodies and CAR T cells for treating poorly differentiated thyroid cancer, showing potent in vitro and in vivo activity.

This study develops bispecific antibodies targeting IGLV3-21R110 to selectively kill high-risk CLL cells while sparing healthy B cells and stem cells.

This study investigates the functional differences between thymic and peripheral Treg cells in visceral adipose tissue, showing that tTreg instability contributes to inflammation and obesity while pTreg cells protect against metabolic disorders.

The paper identifies H3K27me3 regulation of extra-cellular matrix composition in human corticogenesis using Epi-CyTOF and cortical organoids.

The paper benchmarks 23 TCR-epitope prediction models, finding that using paired-chain alpha-beta and CDR1/2/V/J data improves performance, and simple distance-based methods can be competitive.

This paper introduces GERAS, a machine learning framework that classifies single-cell transcriptomes into chronological stages with high accuracy and identifies aging-related factors in zebrafish and human pancreatic cells.