Synthetic BiologyProtein Engineering Design and SelectionPeer-reviewed
Rational design of selective bispecific EPO-R/CD131 agonists
Kailyn E. Doiron, Jeffrey C. Way, Pamela A. Silver
The paper designs bispecific agonists targeting EPO-R/CD131 to selectively activate signaling without engaging EPO-R/EPO-R, validated through structural modeling and functional assays.