Author

Katherine Redfield Chan

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:protein structure· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein design· 1

Frequent Co-Authors

Jeffrey C. WayiD· 3 shared Pamela A. SilveriD· 2 shared A. R. Graveline· 1 shared A. Vernet· 1 shared Andyna VernetiD· 1 shared Camille Elise PoweiD· 1 shared Daniel HeidiD· 1 shared Dominik NiopekiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersSynthetic Biology

Jeffrey C. WayORCID

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3 papers

Recent·Most cited

An Fc-SPINK1 fusion protein inhibits pancreatic inflammation in a mouse model

Jeffrey C. Way, Daniel Heid, M. Theiß, Simon Flyvbjerg Nørrelykke, Lucas Barck, L. Burger, J. A. Bredl, Thorge Dobbertin, P. Höflich, Tobias Stadelmann, Dominik Niopek, Katherine Redfield Chan, R. Sivaraman, A. R. Graveline, A. Vernet, , P. A. Silver

This paper develops an Fc-SPINK1 fusion protein that reduces pancreatic inflammation in mice by extending its half-life and inhibiting trypsin activity.

bioRxiv · Feb 21, 2025 · PreprintPharmacology & Toxicology

A long-acting prolactin to combat lactation insufficiency

Kasia M. Kready, Kailyn E. Doiron, Katherine Redfield Chan, Jeffrey C. Way, Quincey A. Justman, Camille Elise Powe, Pamela A. Silver

This paper engineers a long-acting prolactin variant to enhance lactation, showing it increases milk production and restores pup growth in mice.

bioRxiv · Dec 15, 2023 · PreprintSynthetic Biology

Rational Design of a Bifunctional AND-Gate Ligand to Modulate Cell-Cell Interactions

Jungmin Lee, Andyna Vernet, Katherine Redfield Chan, Shulin Lu, Ionita Calin Ghiran, Jeffrey C. Way, Pamela A. Silver

The paper designs a bifunctional AND-gate ligand to modulate cell-cell interactions by avoiding thrombosis and RBC adhesion.

ACS Synthetic Biology · Dec 13, 2019Peer-reviewedSynthetic Biology