BiochemistrybioRxivPreprint
Nitrogen deletion in the biosynthesis of HDAC-targeting anticancer drugs
Xinyun Jian, Jinlian Zhao, Edward Marschall…·Gregory L. Challis
The paper investigates nitrogen deletion in the biosynthesis of HDAC-targeting anticancer drugs, showing its importance for bioactivity and revealing the enzymatic mechanisms involved.
DOI 10.1101/2025.03.13.642940