Author

Santiago Revale

Centre for Human GeneticsORCID 0000-0001-5219-9582Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Santiago Revale2 papers

Biology Disciplines

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Cancer Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Andrew RamosiD· 1 shared Andy Protheroe· 1 shared Aniko Rendek· 1 shared Anusha RajaniD· 1 shared David Robert MoleiD· 1 shared Edward DrydaleiD· 1 shared Elena Zanchini di Castiglionchio· 1 shared Emmanuel Bugarín-EstradaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

Andrew RamosORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 22, 2025

Hallmarks of adaptive immunity in a metastatic clear cell renal cell carcinoma (ccRCC) long-term elite survivor

Felicia Tucci, Edward Drydale, James M. Bancroft…·Rachael J. M. Bashford-Rogers

This study identifies clonal persistence, tertiary lymphoid structures (TLS) engagement, and coordinated B-T cell immune surveillance as hallmarks of durable tumour control in a long-term survivor of metastatic ccRCC.

DOI 10.64898/2025.12.19.695541

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintFeb 10, 2025

Precise engineering of chimeric antigen receptor expression levels defines T cell identity and function

Andrew Ramos, Sylvain Simon, Jesús A. Siller‐Farfán…·Tatjana Sauka‐Spengler

This study shows that varying CAR expression levels in T cells affects their activation, function, and transcriptional identity, with optimal CAR levels preventing exhaustion.

DOI 10.1101/2025.02.10.637482

𝕏 PostBluesky