Author
University of OxfordORCID 0000-0002-0984-300XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Samvid Kurlekar, Joanna D.C.C. Lima, Niklas Kupfer…·Peter John Ratcliffe
This study investigates how VHL and PBRM1 inactivation cooperate to disrupt epithelial homeostasis and promote ccRCC by analyzing their effects on transcription and tissue structure in vivo.
Felicia Tucci, Edward Drydale, James M. Bancroft…·Rachael J. M. Bashford-Rogers
This study identifies clonal persistence, tertiary lymphoid structures (TLS) engagement, and coordinated B-T cell immune surveillance as hallmarks of durable tumour control in a long-term survivor of metastatic ccRCC.
Joanna D.C.C. Lima, Madeleine Hooker, Ran Li…·Samvid Kurlekar
The paper investigates how HIF1A and HIF2A isoforms drive cell-type specific oncogenesis in VHL disease by analyzing their roles in renal cell proliferation.
María Tiana, Bárbara Acosta‐Iborra, Laura Puente-Santamaría…·Luis del Peso
The paper identifies SIN3A's role in hypoxia-induced transcriptional changes, showing it represses 75% of hypoxia-repressed genes and inhibits 47% of hypoxia-induced genes.