Hawa Racine Thiam

The paper benchmarks three live-cell image metrics for quantifying chromatin organization changes, showing they correlate with chromatin accessibility and track chromatin dynamics in different biological processes.

This study generates human neutrophils from HSCs and shows that migration speed, deformation through constrictions, and recovery from deformation emerge at different stages of differentiation.

The paper investigates how chromatin organization affects cell mechanics during NETosis, finding that chromatin decompaction increases plasma membrane tension and cell volume independently of gene expression.

This study investigates how LL-37 binds to nucleic acids, forming complexes that affect DNA structure and NET clearance, with implications for immune regulation and disease.

The paper identifies ruptoblasts, a novel cytotoxic cell type in planarians, showing they use explosive cell death to release cytotoxic agents in response to activin, linking hormonal regulation to immune defense.

The paper identifies autoantibody hotspots on the XIST RNP complex in female-biased autoimmune diseases and links them to clinical outcomes.