NeuroscienceMolecular PsychiatryPeer-reviewed
Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters
Ernest Palomer, Núria Martín‐Flores, Sarah Jolly…·Patricia C. Salinas
The paper identifies Sirt2-induced H4K16ac deacetylation of Fzd1 and Fzd7 promoters as a mechanism repressing Wnt signaling in Alzheimer's disease.