Philip Greulich

This paper demonstrates that stem cell self-renewal can occur without niche feedback or fine-tuning through a dimerization cycle mechanism.

The paper uses a computational model to show how cell division and fate regulation influence macroscopic cell type patterns in epithelial sheets, revealing different patterns based on signaling and division symmetry.

The paper shows that striatal astrocytes have widespread neurogenic potential that is activated focally after injury, with behavior similar to canonical niches.

This study investigates microglial colonisation during brain development, showing clonal expansion of proliferative progenitors and an allometric scaling of microglia density.

This paper develops a framework to understand lineage architecture and stem cell identity using network science, showing that lineage structures arise from homeostasis and that stemness is context-dependent.

The paper shows that stem cell self-renewal models fall into two universality classes with identical clonal statistics under asymptotic conditions, making it difficult to distinguish between models within the same class using clonal data alone.