ImmunologyImmunityPeer-reviewed
Spermidine/spermine N1-acetyltransferase controls tissue-specific regulatory T cell function in chronic inflammation
Teresa Neuwirth, Daniel Malzl, Katja Knapp…·Georg Stary
The paper identifies SAT1 as a marker of skin-specific Treg dysfunction in TH17-mediated inflammation and shows targeting SSAT can rescue Treg function in a mouse model.