Author

Laure Lecoin

Centre National de la Recherche ScientifiqueORCID 0000-0001-5259-4339Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Alain EychèneiD· 1 shared Armelle RancillaciD· 1 shared Benoît TerrisiD· 1 shared Bertrand DuvilliéiD· 1 shared Cédric MessaoudiiD· 1 shared Célio PouponnotiD· 1 shared Christine PéchouxiD· 1 shared Christine Walczak· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Alain EychèneORCID

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2 papers

Recent·Most cited

Long-projection astrocytes challenge canonical territorial organization in the sleep-promoting VLPO

Félix Camille Bellier, Lou Zonca, Quentin Perrenoud, Leana Razaghi, Laura Dumas, Jason Durand, Laure Lecoin, Karine Loulier, David Holcman, Frédéric Chauveau, Nathalie Rouach, Armelle Rancillac

The paper identifies specialized astrocyte subtypes in the VLPO, including long-projection astrocytes with hominid-like morphology, revealing enhanced glial network integration in a sleep-promoting nucleus.

bioRxiv · Mar 10, 2026 · PreprintNeuroscience

MAFA Phosphorylation Controls Beta-Cell Identity and Sex-Specific Pancreatic Disease Outcomes

Moustapha Ka, Sabine Druillennec, Sara Chabi, Roullé Céline, YX Ng Dave, Christine Péchoux, Cédric Messaoudi, Christine Walczak, Marie‐Noëlle Soler, Laetitia Besse, Laure Lecoin, Sandra Majo, Gradwhol Gérard, Alain Eychène, Benoît Terris, , Bertrand Duvillié

This study shows that MAFA phosphorylation affects beta-cell identity and sex-specific pancreatic disease outcomes in mice, linking phosphorylation defects to diabetes and mucinous cystic neoplasms.

bioRxiv · Jun 11, 2025 · PreprintCell Biology