Benoît Terris

CLONAL LYMPHOCYTE EXPANSIONS AND JAK-STAT PATHWAY MUTATIONS DEFINE A PATHOGENIC CONTINUUM DRIVING RESISTANCE TO GLUTEN-FREE DIET IN CELIAC DISEASE

This study identifies clonal lymphocyte expansions and JAK-STAT mutations in celiac disease subtypes, revealing shared mechanisms and limitations of JAK inhibitor therapy.

The gut insulin receptor acts as gatekeeper of intestinal barrier integrity

This study shows that gut insulin receptor loss increases intestinal permeability and susceptibility to infections by impairing Paneth cell function and intestinal stem cell homeostasis.

MAFA Phosphorylation Controls Beta-Cell Identity and Sex-Specific Pancreatic Disease Outcomes

This study shows that MAFA phosphorylation affects beta-cell identity and sex-specific pancreatic disease outcomes in mice, linking phosphorylation defects to diabetes and mucinous cystic neoplasms.

A macrophage-smooth muscle cell axis influences vascular remodeling through activation of the EGFR pathway in giant cell arteritis